Ua manaʻo kekahi noiʻi hou i ka maʻi pinepine o ka maʻi herpes simplex virus (HSV) a me ka maʻi maʻi maʻi genital (GUD). Hōʻike nā manaʻo hoʻohālikelike ma kahi o 846 miliona mau kānaka he 15-49 mau makahiki e noho nei me nā maʻi herpes genital i 2020, ʻoi aku ia ma mua o 20% o ka poʻe i kēia pūʻulu makahiki ma ka honua holoʻokoʻa. No ka hoʻohālikelike, ʻo ka huina o ka poʻe me ka maʻi herpes genital ma 2016 ma kahi o ka hapalua piliona. ʻO nā kiʻekiʻe kiʻekiʻe o ka ulu ʻana a me ka ulu ʻana o ka makahiki i nā makahiki i hala aku nei e koi ana i nā hana pale ʻoi aku ka maikaʻi. I kēia manawa, ʻaʻohe lāʻau lapaʻau HSV laikini. Nui nā moho kano kano HSV i ka pipeline akā aia nā mea āpau i ke kūlana preclinical, akā e komo i ka pae 1 o ka hoʻokolohua lapaʻau kanaka.
ʻO ka maʻi maʻi Herpes simplex (HSV) he maʻi DNA kaulalua no ka ʻohana herpesviridae. Hoʻopaʻa ia i ka hoʻokipa ʻana i nā kelepona a hana hou i loko o nā ʻiʻo like ʻole e like me nā epithelial cell, neurons, etc. Laha ka maʻi ma o ka pili ʻana i ka ʻili.
ʻO ka maʻi HSV he ola lōʻihi, hiki ke mālama ʻia akā ʻaʻole hiki ke hoʻōla.
ʻElua ʻano o ka HSV. ʻO ka HSV-1 ke kumu nui o ka herpes waha a hoʻolaha ʻia ma o ka hoʻopili waha, akā naʻe hiki ke pili pū i ka maʻi genital a hoʻoili ʻia ma ka moekolohe.
ʻO ka HSV-2 ke kumu o ka maʻi herpes genital a laha ʻia ma o ka hoʻopili ʻana. ʻO ka maʻi ulcer genital (GUD) pili pū me HSV-2 a me HSV-1.
ʻO ka poʻe i loaʻa i ka maʻi HSV, ʻoi aku ka nui o ka HSV-2 i ka loaʻa ʻana o ka maʻi immunodeficiency kanaka (HIV).
Ua ʻike ʻia ka maʻi maʻi Herpes simplex i hoʻopilikia i ka nui o nā kānaka a puni ka honua. I ka makahiki 2016, ua helu ʻia kahi noiʻi i ka helu o ia mau kānaka. Ua ʻike ʻia aia ma kahi o ka hapalua piliona kānaka i loaʻa i ka maʻi genital i pili i ka HSV-2 a me HSV-1 aʻo kekahi mau piliona kānaka i loaʻa i ka maʻi waha ma muli o HSV-1. Eia hou, ua pilikia nā miliona o ka poʻe i loaʻa i ka maʻi immunodeficiency kanaka (HIV).
ʻO kahi noiʻi hou i paʻi ʻia ma ka lā 10 Dekemaba 2024 ua hoʻomālamalama i ka nui o kēia pilikia. Me ka hoʻohana ʻana i kahi hoʻohālike makemakika calibrated a me nā hoʻokomo hoʻohālike mai ka loiloi ʻōnaehana a me nā meta-analyses o ka ʻikepili prevalence HSV no nā wahi āpau o WHO, ua hoʻokumu ʻia ka noiʻi ʻana i nā manaʻo o ka hanana a me ka nui o nā maʻi HSV genital ma ka honua holoʻokoʻa i 2020 i ka makahiki 15-49 mau makahiki. ʻO ka maʻi maʻi maʻi maʻi maʻi (GUD) i hoʻokumu ʻia e nā ʻano HSV ʻelua a me nā maʻi non-genital i hoʻokumu ʻia e HSV-1.
Papa: Ka pinepine o ka maʻi o ka maʻi HSV genital ma 2020 i loko o ka pūʻulu makahiki 15-49.
| Ka helu o na kanaka kahiko 15-49 mau makahiki pili i nā maʻi HSV genital ma ka honua holoʻokoʻa i ka makahiki 2020 |
| ʻO nā maʻi HSV ma muli o ka HSV-2: →25.6 miliona mau hihia hou (ka hopena), →519.5 miliona (a i ʻole 13.3%) ka nui o nā hihia i loaʻa (prevalence) →187.9 miliona me ka liʻiliʻi hoʻokahi manawa o ka maʻi maʻi maʻi maʻi genital (GUD) no HSV-2. |
| ʻO nā maʻi HSV genital ma muli o ka HSV-1: →16.8 miliona mau hihia hou →376.2 miliona (a i ʻole 10.2%) ka nui o nā hihia i loaʻa (prevalence) →16.7 miliona me ka liʻiliʻi hoʻokahi manawa o ka maʻi maʻi maʻi maʻi genital (GUD) no HSV-2. |
| →ʻO 846 miliona ka huina o ka poʻe i piha i ka makahiki 15-49 makahiki e noho ana me nā maʻi herpes genital (ka nui o ka HSV-2 a me ka hoʻonui ʻana o ka HSV-1). ʻOi aku kēia ma mua o 20% o ka poʻe ma kēia pūʻulu makahiki ma ka honua. →ʻO 204.6 miliona ka huina o ka poʻe i piha i ka makahiki 15-49 me ka liʻiliʻi o hoʻokahi manawa o ka GUD pili i ka HSV. →Ma kahi o 42 miliona mau kānaka e loaʻa i nā maʻi herpes genital hou i kēlā me kēia makahiki. |
| (Kumu: Harfouche M., ¶ AL 2024) |
E like me ka noiʻi hou ʻana, he 846 miliona mau kānaka o 15-49 mau makahiki e noho nei me nā maʻi herpes genital (ma muli o HSV-2 a me HSV-1) i ka makahiki 2020. No ka hoʻohālikelike ʻana, ma 2016, ma kahi o ka hapalua miliona mau kānaka. (i nā pūʻulu makahiki a pau) loaʻa ka maʻi herpes genital.
ʻIke loa, he kiʻekiʻe loa ka nui o nā maʻi HSV genital a me nā helu prevalence. I ka makahiki 2020, ʻoi aku ma mua o 20% o ka poʻe i ka makahiki 15-49 mau makahiki i loaʻa i ka maʻi herpes genital. ʻO ka mea hopohopo, ua piʻi ka helu i ka wikiwiki i nā makahiki i hala iho nei.
Pono ke kūlana no ka pale ʻana a me ka maikaʻi kaukaʻi ana. I kēia manawa, ʻaʻohe lāʻau lapaʻau HSV laikini. Nui nā moho kano kano HSV i ka pipeline akā aia nā mea āpau i ke kūlana preclinical, akā e komo i ka pae 1 o ka hoʻokolohua lapaʻau kanaka.
***
E hoʻomaopopo ':
- WHO. Pepa ʻoiaʻiʻo - Herpes simplex virus. 10 Kekemapa 2024. Loaʻa ma https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus
- James, Charlotte et al. "Herpes simplex virus: ka nui o ka maʻi maʻi honua a me nā helu kuhi, 2016." Bulletin of the World Health Organization vol. 98,5 (2020): 315-329. Loaʻa ma https://pmc.ncbi.nlm.nih.gov/articles/PMC7265941/
- Harfouche M., et al 2024. Ua manaʻo ʻia ka ulu ʻana o ka honua a me ka āpana a me ka nui o nā maʻi maʻi herpes simplex a me ka maʻi maʻi maʻi maʻi maʻi ma 2020: nā loiloi hoʻohālike makemakika. ʻO nā maʻi i hoʻouna ʻia ma ke kino, BMJ Journals. Published Online First: 10 December 2024. DOI: https://doi.org/10.1136/sextrans-2024-056307
- Nūhou WHO- Ma luna o 1 i loko o 5 mau mākua ma ka honua holoʻokoʻa i loaʻa i ka maʻi herpes genital - WHO. Hoʻopuka ʻia 11 Dekemaba 2024. Loaʻa ma https://www.who.int/news/item/11-12-2024-over-1-in-5-adults-worldwide-has-a-genital-herpes-infection-who
- WHO. Ka La'i Ka'i 'Ai, Vaccines and Biologicals - Herpes Simplex Virus. Loaʻa ma https://www.who.int/teams/immunization-vaccines-and-biologicals/diseases/herpes-simplex-virus
***
